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1

A new generation of starch products as excipient in pharmaceutical tablets. I. Preparation and binding properties of high surface area potato starch products

G.H.P. te Wierik, J. Bergsma, A.W. Arends-Scholte, T. Boersma, A.C. Eissens, C.F. Lerk

Journal:

International Journal of Pharmaceutics

Year:

1996

Language:

english

File:

PDF, 537 KB

english, 1996

2

Effect of hydrophilization of hydrophobic drugs on release rate from capsules

C. F. Lerk, M. Lagas, J. T. Fell, P. Nauta

Journal:

Journal of Pharmaceutical Sciences

Year:

1978

Language:

english

File:

PDF, 624 KB

english, 1978

3

Development and optimization of pharmaceutical formulations using a simplex lattice design

R. Huisman, H. V. Van Kamp, J. W. Weyland, D. A. Doornbos, G. K. Bolhuis, C. F. Lerk

Journal:

International Journal of Clinical Pharmacy

Year:

1984

Language:

english

File:

PDF, 800 KB

english, 1984

4

The relationship between bulk density and compactibility of lactose granulations

K. Zuurman, K.A. Riepma, G.K. Bolhuis, H. Vromans, C.F. Lerk

Journal:

International Journal of Pharmaceutics

Year:

1994

Language:

english

File:

PDF, 840 KB

english, 1994

5

Contact angles and wetting of pharmaceutical powders

C. F. Lerk, A. J. M. Schoonen, J. T. Fell

Journal:

Journal of Pharmaceutical Sciences

Year:

1976

Language:

english

File:

PDF, 517 KB

english, 1976

6

Contact angles of pharmaceutical powders

C. F. Lerk, M. Lagas, J. P. Boelstra, P. Broersma

Journal:

Journal of Pharmaceutical Sciences

Year:

1977

Language:

english

File:

PDF, 204 KB

english, 1977

7

In vitro and in vivo availability of hydrophilized phenytoin from capsules

C. F. Lerk, M. Lagas, L. Lie-A-Huen, P. Broersma, K. Zuurman

Journal:

Journal of Pharmaceutical Sciences

Year:

1979

Language:

english

File:

PDF, 507 KB

english, 1979

8

Interaction of tablet disintegrants and magnesium stearate during mixing I: Effect on tablet disintegration

G. K. Bolhuis, A. J. Smallenbroek, C. F. Lerk

Journal:

Journal of Pharmaceutical Sciences

Year:

1981

Language:

english

File:

PDF, 323 KB

english, 1981

9

Multivariate modelling of the tablet manufacturing process with wet granulation for tablet optimization and in-process control

Johan A Westerhuis, Pierre M.J Coenegracht, Coenraad F Lerk

Journal:

International Journal of Pharmaceutics

Year:

1997

Language:

english

File:

PDF, 126 KB

english, 1997

10

Physikalisch-pharmazeutische Eigenschaften von Lactose

Prof. Dr. Ir. Coenraad F. Lerk

Journal:

Pharmazie in unserer Zeit

Year:

1987

Language:

german

File:

PDF, 1.01 MB

german, 1987

11

Native starch in tablet formulations: Properties on compaction

C. E. Bos, G. K. Bolhuis, H. van Doorne, C. F. Lerk

Journal:

International Journal of Clinical Pharmacy

Year:

1987

Language:

english

File:

PDF, 1.68 MB

english, 1987

12

The effect of particle size of disintegrants on the disintegration of tablets

A. J. Smallenbroek, G. K. Bolhuis, C. F. Lerk

Journal:

International Journal of Clinical Pharmacy

Year:

1981

Language:

english

File:

PDF, 316 KB

english, 1981

13

Increased gastro-intestinal absorption of hexobarbital by hydrophilization

M. Lagas, C. F. Lerk, D. D. Breimer

Journal:

International Journal of Clinical Pharmacy

Year:

1980

Language:

english

File:

PDF, 535 KB

english, 1980

14

Studies on tableting properties of lactose

H. Vromans, A. H. De Boer, G. K. Bolhuis, C. F. Lerk, K. D. Kussendrager, H. Bosch

Journal:

International Journal of Clinical Pharmacy

Year:

1985

Language:

english

File:

PDF, 631 KB

english, 1985

15

Consolidation and compaction of powder mixtures. I. Binary mixtures of same particle size fractions of different types of crystalline lactose

K.A. Riepma, C.F. Lerk, A.H. de Boer, G.K. Bolhuis, K.D. Kussendrager

Journal:

International Journal of Pharmaceutics

Year:

1990

Language:

english

File:

PDF, 463 KB

english, 1990

16

A coherent matrix model for the consolidation and compaction of an excipient with magnesium stearate

K.A. Riepma, H. Vromans, C.F. Lerk

Journal:

International Journal of Pharmaceutics

Year:

1993

Language:

english

File:

PDF, 1.09 MB

english, 1993

17

The effect of storage at ambient humidity on the BET-specific surface area of tablets compacted from different materials

K.A. Riepma, E.G. Dekker, R.S. Jager, P.A. Elberse, C.F. Lerk

Journal:

International Journal of Pharmaceutics

Year:

1993

Language:

english

File:

PDF, 282 KB

english, 1993

18

Application of sucrose laurate in topical preparations of cyclosporin A

P.C. Lerk, H. Sucker

Journal:

International Journal of Pharmaceutics

Year:

1993

Language:

english

File:

PDF, 781 KB

english, 1993

19

Effect of water on deformation and bonding of pregelatinized starch compacts

Kees Van der Voort Maarschalk, Herman Vromans, Willem Groenendijk, Gerad K. Bolhuis, Coenraad F. Lerk

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

1997

Language:

english

File:

PDF, 591 KB

english, 1997

20

Relation between crushing strength and internal specific surface area of lactose compacts

LEUENBERGER, H, BONNY, J, LERK, C, VROMANS, H

Journal:

International Journal of Pharmaceutics

Year:

1989

Language:

english

File:

PDF, 514 KB

english, 1989

21

Evaluation of modified rice starch, a new excipient for direct compression.

Bos, C. E., Bolhuis, G. K., Lerk, C. F., Duineveld, C. A.A.

Journal:

Drug Development and Industrial Pharmacy

Year:

1992

Language:

english

File:

PDF, 916 KB

english, 1992

22

Severe Plastic Deformation Processes with Friction Induced Shear

Lapovok, Rimma, Estrin, Yuri, Djugum, Richard, Lerk, Andre

Journal:

Materials Science Forum

Year:

2010

Language:

english

File:

PDF, 779 KB

english, 2010

23

Geschichte der deutschen Literatur: Von den Anfangen bis zur Gegenwart

Zimmermann, Ulf, Saalfeld, Lerke von, Kreidt, Dietrich, Rothe, Friedrich

Journal:

World Literature Today

Year:

1990

Language:

english

File:

PDF, 394 KB

english, 1990

24

Investigation of the effect of gamma rays on the properties of polyamide fibres, I. The changes of some mechanical and chemical properties

W. Szymański, G. Lerke, B. Rymian

Journal:

Macromolecular Materials and Engineering

Year:

1981

Language:

english

File:

PDF, 406 KB

english, 1981

25

Radiation yield of hydrogen chloride in gamma-irradiated poly(vinyl chloride) stabilized by epoxy compounds

I. Lerke, W. Szymański

Journal:

Journal of Applied Polymer Science

Year:

1977

Language:

english

File:

PDF, 373 KB

english, 1977

26

Stabilization of gamma-irradiated poly(vinyl chloride) by epoxy compounds. I. Radiation yield of hydrogen chloride and changes of epoxy group concentration in gamma-irradiated PVC–stabilizer mixtures

G. Lerke, I. Lerke, W. Szymański

Journal:

Journal of Applied Polymer Science

Year:

1983

Language:

english

File:

PDF, 500 KB

english, 1983

27

Stabilization of gamma-irradiated poly(vinyl chloride) by epoxy compounds. II. Production of hydroperoxides in gamma-irradiated PVC–stabilizer mixtures

I. Lerke, W. Szymański

Journal:

Journal of Applied Polymer Science

Year:

1983

Language:

english

File:

PDF, 278 KB

english, 1983

28

Stabilization of gamma-irradiated poly(vinyl chloride) by epoxy compounds. III. Conjugated double bonds and degree of unsaturation in gamma-irradiated PVC–stabilizer mixtures

G. Lerke, I. Lerke, W. Szymański

Journal:

Journal of Applied Polymer Science

Year:

1983

Language:

english

File:

PDF, 489 KB

english, 1983

29

Densification Behaviour of Powder Mixtures in Relation to their Binding Properties

Dr. Herman Vromans, Prof. Dr. Ir. Coenraad F. Lerk

Journal:

Chemie Ingenieur Technik

Year:

1989

Language:

english

File:

PDF, 199 KB

english, 1989

30

Effect of microcrystalline cellulose on liquid penetration in and disintegration of directly compressed tablets

C. F. Lerk, G. K. Bolhuis, A. H. de Boer

Journal:

Journal of Pharmaceutical Sciences

Year:

1979

Language:

english

File:

PDF, 768 KB

english, 1979

31

Transitions of lactoses by mechanical and thermal treatment

C. F. Lerk, A. C. Andreae, A. H. de Boer, P. De Hoog, K. Kussendrager, J. Van Leverink

Journal:

Journal of Pharmaceutical Sciences

Year:

1984

Language:

english

File:

PDF, 300 KB

english, 1984

32

Alterations of α-lactose during differential scanning calorimetry

C. F. Lerk, A. C. Andreae, A. H. de Boer, P. de Hoog, K. Kussendrager, J. van Leverink

Journal:

Journal of Pharmaceutical Sciences

Year:

1984

Language:

english

File:

PDF, 208 KB

english, 1984

33

Theoretical analysis of the release of drug from completely dissolving carriers containing drug particles

P. de Haan, C. F. Lerk

Journal:

Journal of Pharmaceutical Sciences

Year:

1988

Language:

english

File:

PDF, 495 KB

english, 1988

34

The velocity and stability of large porosity fluctuations in homogeneous fluidized systems

J. Verloop, P.M. Heertjes, L.A. Lerk

Journal:

Chemical Engineering Science

Year:

1974

Language:

english

File:

PDF, 462 KB

english, 1974

35

Digital simulation of the square scheme in cyclic voltammetry: A comparison of methods

Susan A. Lerke, Dennis H. Evans, Stephen W. Feldberg

Journal:

Journal of Electroanalytical Chemistry and Interfacial Electrochemistry

Year:

1990

Language:

english

File:

PDF, 999 KB

english, 1990

36

Voltammetric study of the oxidation of metal derivatives of buckminsterfullerence (C60)

Susan A. Lerke, Dennis H. Evans, Paul J. Fagan

Journal:

Journal of Electroanalytical Chemistry

Year:

1995

Language:

english

File:

PDF, 487 KB

english, 1995

37

Cyclodextrin-facilitated bioconversion of 17β-estradiol by a phenoloxidase from Mucuna pruriens cell cultures

Herman J. Woerdenbag, Niesko Pras, Henderik W. Frijlink, Coenraad F. Lerk, Theo M. Malingré

Journal:

Year:

1990

Language:

english

File:

PDF, 421 KB

english, 1990

38

Polymers with improved short term hemocompatibility obtained by radiation grafting of N-vinylpyrrolidone onto silicone rubber

A. Chapiro, M. Foex-Millequant, A.-M. Jendrychowska-Bonamour, Y. Lerke, P. Sadurni, D. Domurado

Journal:

Radiation Physics and Chemistry (1977)

Year:

1977

Language:

english

File:

PDF, 333 KB

english, 1977

39

Development of a potentially wearable glucose sensor for patients with diabetes mellitus: design and in-vitro evaluation

A.J.M. Schoonen, F.J. Schmidt, H. Hasper, D.A. Verbrugge, R.G. Tiessen, C.F. Lerk

Journal:

Biosensors and Bioelectronics

Year:

1990

Language:

english

File:

PDF, 566 KB

english, 1990

40

Plasticisation of amylodextrin by moisture: Consequences for drug release from tablets

Rob Steendam, Anco C.E Eissens, Henderik W Frijlink, Coenraad F Lerk

Journal:

International Journal of Pharmaceutics

Year:

2000

Language:

english

File:

PDF, 387 KB

english, 2000

41

Stress relaxation of compacts produced from viscoelastic materials

K. Van der Voort Maarschalk, K. Zuurman, H. Vromans, G.K. Bolhuis, C.F. Lerk

Journal:

International Journal of Pharmaceutics

Year:

1997

Language:

english

File:

PDF, 576 KB

english, 1997

42

Poly(dl-lactic acid) as a direct compression excipient in controlled release tablets: Part I. Compaction behaviour and release characteristics of poly(dl-lactic acid) matrix tablets

R. Steendam, C.F. Lerk

Journal:

International Journal of Pharmaceutics

Year:

1998

Language:

english

File:

PDF, 1.53 MB

english, 1998

43

NMR characterization of a novel bile acid sequestrant, DMP 504

Susan A Lerke, Gregory Nemeth, Ernest Schubert, Paul K Hovsepian

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Year:

2001

Language:

english

File:

PDF, 113 KB

english, 2001

44

Increased podophyllotoxin production inPodophyllum hexandrumcell suspension cultures after feeding coniferyl alcohol as a β-cyclodextrin complex

Herman J. Woerdenbag, Wim Uden, Henderik W. Frijlink, Coenraad F. Lerk, Niesko Pras, Theo M. Malingré

Journal:

Plant Cell Reports

Year:

1990

Language:

english

File:

PDF, 426 KB

english, 1990

45

Intratumoural administration of cisplatin in slow-release devices

Marc J. M. Deurloo, Sieb Bohlken, Wim Kop, Coenraad F. Lerk, Wim Hennink, Harry Bartelink, Adrian C. Begg

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1990

Language:

english

File:

PDF, 660 KB

english, 1990

46

Optimization of a formulation for direct compression using a simplex lattice design

Herman V. van Kamp, Gerad K. Bolhuis, Coenraad F. Lerk

Journal:

International Journal of Clinical Pharmacy

Year:

1987

Language:

english

File:

PDF, 694 KB

english, 1987

47

Oral controlled release dosage forms. A review

P. de Haan, C. F. Lerk

Journal:

International Journal of Clinical Pharmacy

Year:

1984

Language:

english

File:

PDF, 1.13 MB

english, 1984

48

Abstracts of papers

D. J. A. Crommelin', F. van Dalen, G. F. A. Kersten, A. M. H. van der Put, T. Teerlink, E. C. Beuvery, A. H. de Boer, H. Vromans, C. F. Lerk, P. de Haan, M. F. Saettone, B. Giannaccini, L. Naber, H. W

Journal:

International Journal of Clinical Pharmacy

Year:

1987

Language:

english

File:

PDF, 131 KB

english, 1987

49

Studies on different dissolution models

P. De Haan, C. F. Lerk

Journal:

International Journal of Clinical Pharmacy

Year:

1982

Language:

english

File:

PDF, 602 KB

english, 1982

50

Novel techniques for determination of antibacterial activity of silver sulfanilamides

J. J. M. Van Saene, A. Bult, C. F. Lerk

Journal:

International Journal of Clinical Pharmacy

Year:

1983

Language:

english

File:

PDF, 248 KB

english, 1983